Noninvasive Magnetic Resonance Imaging Detection of Cerebral Amyloid Angiopathy-Related Microvascular Alterations Using Superparamagnetic Iron Oxide Particles in APP Transgenic Mouse Models of Alzheimer's Disease: Application to Passive Aβ Immunotherapy

Cerebral amyloid angiopathy (CAA) is a common feature of Alzheimer's disease (AD). More advanced stages are accompanied by microhemorrhages and vasculitis. Peripheral blood-borne macrophages are intimately linked to cerebrovascular pathology coincident with AD. Magnetic resonance imaging (MRI)...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Beckmann, Nicolau, Gérard, Christelle, Abramowski, Dorothée, Cannet, Catherine, Staufenbiel, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6632947/
https://ncbi.nlm.nih.gov/pubmed/21248127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4936-10.2011
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