The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice

BACKGROUND: The deposition of the amyloid β-peptide (Aβ) in the brain is one of the hallmarks of Alzheimer’s disease (AD). It is not yet clear whether Aβ always leads to similar changes or whether it induces different features of neurodegeneration in relation to its intra- and/or extracellular local...

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Autors principals: Rijal Upadhaya, Ajeet, Scheibe, Frederik, Kosterin, Irina, Abramowski, Dorothee, Gerth, Janina, Kumar, Sathish, Liebau, Stefan, Yamaguchi, Haruyasu, Walter, Jochen, Staufenbiel, Matthias, Thal, Dietmar Rudolf
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046770/
https://ncbi.nlm.nih.gov/pubmed/24252227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-77
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