The type of Aβ-related neuronal degeneration differs between amyloid precursor protein (APP23) and amyloid β-peptide (APP48) transgenic mice

BACKGROUND: The deposition of the amyloid β-peptide (Aβ) in the brain is one of the hallmarks of Alzheimer’s disease (AD). It is not yet clear whether Aβ always leads to similar changes or whether it induces different features of neurodegeneration in relation to its intra- and/or extracellular local...

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Autori principali: Rijal Upadhaya, Ajeet, Scheibe, Frederik, Kosterin, Irina, Abramowski, Dorothee, Gerth, Janina, Kumar, Sathish, Liebau, Stefan, Yamaguchi, Haruyasu, Walter, Jochen, Staufenbiel, Matthias, Thal, Dietmar Rudolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046770/
https://ncbi.nlm.nih.gov/pubmed/24252227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-1-77
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