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Substrate Deconstruction and the Nonadditivity of Enzyme Recognition
[Image: see text] Predicting substrates for enzymes of unknown function is a major postgenomic challenge. Substrate discovery, like inhibitor discovery, is constrained by our ability to explore chemotypes; it would be expanded by orders of magnitude if reactive sites could be probed with fragments r...
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| 主要な著者: | , , , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2014
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4046767/ https://ncbi.nlm.nih.gov/pubmed/24791931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja501354q |
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