Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes

AIMS: The present study was to investigate the role of calpain in reactive oxygen species (ROS) production in endothelial cells and endothelium-dependent vascular dysfunction under experimental conditions of diabetes. METHODS AND RESULTS: Exposure to high glucose activated calpain, induced apoptosis...

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Autors principals: Chen, Bainian, Zhao, Qing, Ni, Rui, Tang, Futian, Shan, Limei, Cepinskas, Inga, Cepinskas, Gediminas, Wang, Wang, Schiller, Peter W, Peng, Tianqing
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045988/
https://ncbi.nlm.nih.gov/pubmed/24886224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-13-88
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