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Re-examining how complexin inhibits neurotransmitter release

Complexins play activating and inhibitory functions in neurotransmitter release. The complexin accessory helix inhibits release and was proposed to insert into SNARE complexes to prevent their full assembly. This model was supported by ‘superclamp’ and ‘poor-clamp’ mutations that enhanced or decreas...

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Библиографические подробности
Главные авторы: Trimbuch, Thorsten, Xu, Junjie, Flaherty, David, Tomchick, Diana R, Rizo, Josep, Rosenmund, Christian
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040926/
https://ncbi.nlm.nih.gov/pubmed/24842998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02391
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