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Re-examining how complexin inhibits neurotransmitter release

Complexins play activating and inhibitory functions in neurotransmitter release. The complexin accessory helix inhibits release and was proposed to insert into SNARE complexes to prevent their full assembly. This model was supported by ‘superclamp’ and ‘poor-clamp’ mutations that enhanced or decreas...

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Detalhes bibliográficos
Main Authors: Trimbuch, Thorsten, Xu, Junjie, Flaherty, David, Tomchick, Diana R, Rizo, Josep, Rosenmund, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040926/
https://ncbi.nlm.nih.gov/pubmed/24842998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02391
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