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Re-examining how complexin inhibits neurotransmitter release

Complexins play activating and inhibitory functions in neurotransmitter release. The complexin accessory helix inhibits release and was proposed to insert into SNARE complexes to prevent their full assembly. This model was supported by ‘superclamp’ and ‘poor-clamp’ mutations that enhanced or decreas...

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Bibliografske podrobnosti
Main Authors: Trimbuch, Thorsten, Xu, Junjie, Flaherty, David, Tomchick, Diana R, Rizo, Josep, Rosenmund, Christian
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040926/
https://ncbi.nlm.nih.gov/pubmed/24842998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02391
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