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Glutathione peroxidase activity is neuroprotective in models of Huntington’s disease
Huntington’s disease (HD) is a fatal neurodegenerative disorder caused by a CAG repeat expansion encoding a polyglutamine tract in the huntingtin (htt) protein(1). Here, we report a genome-wide overexpression suppressor screen which identified 317 open reading frames that ameliorate toxicity of a mu...
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| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4040417/ https://ncbi.nlm.nih.gov/pubmed/23974869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2732 |
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