Protein Kinase C-η Controls CTLA-4-Mediated Regulatory T Cell Function

Regulatory T cells (T(reg) cells), which maintain immune homeostasis and self-tolerance, form an immunological synapse (IS) with antigen-presenting cells (APCs). However, signaling events at the T(reg) IS remain unknown. Here we show that protein kinase C-η (PKC-η) associated with CTLA-4 and was rec...

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Main Authors: Kong, Kok-Fai, Fu, Guo, Zhang, Yaoyang, Yokosuka, Tadashi, Casas, Javier, Canonigo-Balancio, Ann J., Becart, Stephane, Kim, Gisen, Yates, John R., Kronenberg, Mitchell, Saito, Takashi, Gascoigne, Nicholas R. J., Altman, Amnon
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4040250/
https://ncbi.nlm.nih.gov/pubmed/24705298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2866
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