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Association of the EF-hand and PH domains of the guanine nucleotide exchange factor SLAT with IP(3) receptor 1 promotes Ca(2+) signaling in T cells

The guanine nucleotide exchange factor SLAT (SWAP-70–like adaptor of T cells) regulates T cell activation and differentiation by enabling Ca(2+) release from intracellular stores in response to stimulation of the T cell receptor (TCR). We found a TCR-induced association between SLAT and inositol 1,4...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Signal
Egile Nagusiak: Fos, Camille, Becart, Stephane, Canonigo Balancio, Ann J., Boehning, Darren, Altman, Amnon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300114/
https://ncbi.nlm.nih.gov/pubmed/25270259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005565
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