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Requirement of Treg-intrinsic CTLA4/PKCη signaling pathway for suppressing tumor immunity
The ability of Tregs to control the development of immune responses is essential for maintaining immune system homeostasis. However, Tregs also inhibit the development of efficient antitumor responses. Here, we explored the characteristics and mechanistic basis of the Treg-intrinsic CTLA4/PKCη signa...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752292/ https://ncbi.nlm.nih.gov/pubmed/29212947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95692 |
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