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Requirement of Treg-intrinsic CTLA4/PKCη signaling pathway for suppressing tumor immunity
The ability of Tregs to control the development of immune responses is essential for maintaining immune system homeostasis. However, Tregs also inhibit the development of efficient antitumor responses. Here, we explored the characteristics and mechanistic basis of the Treg-intrinsic CTLA4/PKCη signa...
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| Pubblicato in: | JCI Insight |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5752292/ https://ncbi.nlm.nih.gov/pubmed/29212947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95692 |
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