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Protein kinase C-eta deficiency does not impair antiviral immunity and CD8(+) T cell activation
We reported that protein kinase C-eta (PKCη) forms a novel signaling complex with the checkpoint inhibitory protein CTLA-4 in regulatory T cells (Tregs). This complex is required for the contact-dependent suppressive activity of Tregs, including suppression of anti-tumor immunity. However, the impor...
Gardado en:
| Publicado en: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7373375/ https://ncbi.nlm.nih.gov/pubmed/32198145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900963 |
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