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Requirement of Treg-intrinsic CTLA4/PKCη signaling pathway for suppressing tumor immunity

The ability of Tregs to control the development of immune responses is essential for maintaining immune system homeostasis. However, Tregs also inhibit the development of efficient antitumor responses. Here, we explored the characteristics and mechanistic basis of the Treg-intrinsic CTLA4/PKCη signa...

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Foilsithe in:JCI Insight
Main Authors: Pedros, Christophe, Canonigo-Balancio, Ann J., Kong, Kok-Fai, Altman, Amnon
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752292/
https://ncbi.nlm.nih.gov/pubmed/29212947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.95692
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