T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster

Por Varma, Rajat, Campi, Gabriele, Yokosuka, Tadashi, Saito, Takashi, Dustin, Michael L.
Publicado em 2006

T-Cell Receptor Microclusters Critical for T-Cell Activation Are Formed Independently of Lipid Raft Clustering

Por Hashimoto-Tane, Akiko, Yokosuka, Tadashi, Ishihara, Chitose, Sakuma, Machie, Kobayashi, Wakana, Saito, Takashi
Publicado em 2010

Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2

Por Yokosuka, Tadashi, Takamatsu, Masako, Kobayashi-Imanishi, Wakana, Hashimoto-Tane, Akiko, Azuma, Miyuki, Saito, Takashi
Publicado em 2012

A novel motif in the V3 domain of PKC-θ determines its immunological synapse localization and functions in T cells via association with CD28

Por Kong, Kok-Fai, Yokosuka, Tadashi, Canonigo-Balancio, Ann J., Isakov, Noah, Saito, Takashi, Altman, Amnon
Publicado em 2011

Micro–adhesion rings surrounding TCR microclusters are essential for T cell activation

Por Hashimoto-Tane, Akiko, Sakuma, Machie, Ike, Hiroshi, Yokosuka, Tadashi, Kimura, Yayoi, Ohara, Osamu, Saito, Takashi
Publicado no J Exp Med (2016)

Spatiotemporal regulation of T cell co-stimulation by TCR-CD28 microclusters through PKCθ translocation

Por Yokosuka, Tadashi, Kobayashi, Wakana, Sakata-Sogawa, Kumiko, Hashimoto-Tane, Akiko, Dustin, Michel L., Tokunaga, Makio, Saito, Takashi
Publicado em 2008

Predominant Role of T Cell Receptor (TCR)-α Chain in Forming Preimmune TCR Repertoire Revealed by Clonal TCR Reconstitution System

Por Yokosuka, Tadashi, Takase, Kan, Suzuki, Misao, Nakagawa, Yohko, Taki, Shinsuke, Takahashi, Hidemi, Fujisawa, Takehiko, Arase, Hisashi, Saito, Takashi
Publicado em 2002

CIN85 drives B cell responses by linking BCR signals to the canonical NF-κB pathway

Por Kometani, Kohei, Yamada, Takayuki, Sasaki, Yoshiteru, Yokosuka, Tadashi, Saito, Takashi, Rajewsky, Klaus, Ishiai, Masamichi, Hikida, Masaki, Kurosaki, Tomohiro
Publicado em 2011

NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling

Por Ohtsuka, Makoto, Arase, Hisashi, Takeuchi, Arata, Yamasaki, Sho, Shiina, Ritsuko, Suenaga, Tadahiro, Sakurai, Daiju, Yokosuka, Tadashi, Arase, Noriko, Iwashima, Makio, Kitamura, Toshio, Moriya, Hideshige, Saito, Takashi
Publicado em 2004

Protein Kinase C-η Controls CTLA-4-Mediated Regulatory T Cell Function

Por Kong, Kok-Fai, Fu, Guo, Zhang, Yaoyang, Yokosuka, Tadashi, Casas, Javier, Canonigo-Balancio, Ann J., Becart, Stephane, Kim, Gisen, Yates, John R., Kronenberg, Mitchell, Saito, Takashi, Gascoigne, Nicholas R. J., Altman, Amnon
Publicado em 2014