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T-Cell Receptor Microclusters Critical for T-Cell Activation Are Formed Independently of Lipid Raft Clustering

We studied the function of lipid rafts in generation and signaling of T-cell receptor microclusters (TCR-MCs) and central supramolecular activation clusters (cSMACs) at immunological synapse (IS). It has been suggested that lipid raft accumulation creates a platform for recruitment of signaling mole...

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Detalhes bibliográficos
Main Authors: Hashimoto-Tane, Akiko, Yokosuka, Tadashi, Ishihara, Chitose, Sakuma, Machie, Kobayashi, Wakana, Saito, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897564/
https://ncbi.nlm.nih.gov/pubmed/20498282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00160-10
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