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Spatiotemporal regulation of T cell co-stimulation by TCR-CD28 microclusters through PKCθ translocation
T cell activation is mediated by microclusters (MCs) containing TCRs, kinases, and adaptors. Although TCR-MCs translocate to form a central supramolecular activation cluster (c-SMAC) of immunological synapse between T cells and antigen-presenting cells (APCs), the role of MC translocation in T cell...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2950619/ https://ncbi.nlm.nih.gov/pubmed/18848472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.011 |
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