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Spatiotemporal regulation of T cell co-stimulation by TCR-CD28 microclusters through PKCθ translocation

T cell activation is mediated by microclusters (MCs) containing TCRs, kinases, and adaptors. Although TCR-MCs translocate to form a central supramolecular activation cluster (c-SMAC) of immunological synapse between T cells and antigen-presenting cells (APCs), the role of MC translocation in T cell...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yokosuka, Tadashi, Kobayashi, Wakana, Sakata-Sogawa, Kumiko, Hashimoto-Tane, Akiko, Dustin, Michel L., Tokunaga, Makio, Saito, Takashi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950619/
https://ncbi.nlm.nih.gov/pubmed/18848472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.08.011
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