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Predominant Role of T Cell Receptor (TCR)-α Chain in Forming Preimmune TCR Repertoire Revealed by Clonal TCR Reconstitution System

The CDR3 regions of T cell receptor (TCR)-α and -β chains play central roles in the recognition of antigen (Ag)-MHC complex. TCR repertoire is created on the basis of Ag recognition specificity by CDR3s. To analyze the potential spectrum of TCR-α and -β to exhibit Ag specificity and generate TCR rep...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yokosuka, Tadashi, Takase, Kan, Suzuki, Misao, Nakagawa, Yohko, Taki, Shinsuke, Takahashi, Hidemi, Fujisawa, Takehiko, Arase, Hisashi, Saito, Takashi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193687/
https://ncbi.nlm.nih.gov/pubmed/11956290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20010809
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