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Expansion of the Preimmune Antibody Repertoire by Junctional Diversity in Bos taurus

Cattle have a limited range of immunoglobulin genes which are further diversified by antigen independent somatic hypermutation in fetuses. Junctional diversity generated during somatic recombination contributes to antibody diversity but its relative significance has not been comprehensively studied....

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Detalhes bibliográficos
Main Authors: Liljavirta, Jenni, Niku, Mikael, Pessa-Morikawa, Tiina, Ekman, Anna, Iivanainen, Antti
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4057420/
https://ncbi.nlm.nih.gov/pubmed/24926997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099808
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