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Depolarization Controls TRAIL-Sensitization and Tumor-Selective Killing of Cancer Cells: Crosstalk with ROS

Conventional genotoxic anti-cancer drugs target the proliferative advantage of tumor cells over normal cells. This kind of approach lacks the selectivity of treatment to cancer cells, because most of the targeted pathways are essential for the survival of normal cells. As a result, traditional cance...

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Autors principals: Suzuki-Karasaki, Yoshihiro, Suzuki-Karasaki, Miki, Uchida, Mayumi, Ochiai, Toyoko
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038927/
https://ncbi.nlm.nih.gov/pubmed/24910845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00128
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