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Autophagy inhibitors regulate TRAIL sensitivity in human malignant cells by targeting the mitochondrial network and calcium dynamics

In a variety of cancer cell types, the pharmacological and genetic blockade of autophagy increases apoptosis induced by various anticancer drugs. These observations suggest that autophagy counteracts drug-induced apoptosis. We previously reported that in human melanoma and osteosarcoma cells, autoph...

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Detalhes bibliográficos
Publicado no:Int J Oncol
Main Authors: Onoe-Takahashi, Asuka, Suzuki-Karasaki, Manami, Suzuki-Karasaki, Miki, Ochiai, Toyoko, Suzuki-Karasaki, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438429/
https://ncbi.nlm.nih.gov/pubmed/30896851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2019.4760
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