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Depolarization Controls TRAIL-Sensitization and Tumor-Selective Killing of Cancer Cells: Crosstalk with ROS

Conventional genotoxic anti-cancer drugs target the proliferative advantage of tumor cells over normal cells. This kind of approach lacks the selectivity of treatment to cancer cells, because most of the targeted pathways are essential for the survival of normal cells. As a result, traditional cance...

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Detalhes bibliográficos
Main Authors: Suzuki-Karasaki, Yoshihiro, Suzuki-Karasaki, Miki, Uchida, Mayumi, Ochiai, Toyoko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038927/
https://ncbi.nlm.nih.gov/pubmed/24910845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00128
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