Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: Role for ATP-sensitive K(+) channels and endoplasmic reticulum stress

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is promising for cancer treatment owing to its selective cytotoxicity against malignant cells. However, some cancer cell types, including malignant melanoma cells, are resistant to TRAIL-induced apoptosis. Therefore, drugs that can ampl...

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Main Authors: SUZUKI, YOSHIHIRO, INOUE, TOSHIO, MURAI, MAYUMI, SUZUKI-KARASAKI, MIKI, OCHIAI, TOYOKO, RA, CHISEI
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582902/
https://ncbi.nlm.nih.gov/pubmed/22613960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2012.1483
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