A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase

The quinoline-based allosteric HIV-1 integrase (IN) inhibitors (ALLINIs) are promising candidates for clinically useful antiviral agents. Studies using these compounds have highlighted the role of IN in both early and late stages of virus replication. However, dissecting the exact mechanism of actio...

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Hauptverfasser: Sharma, Amit, Slaughter, Alison, Jena, Nivedita, Feng, Lei, Kessl, Jacques J., Fadel, Hind J., Malani, Nirav, Male, Frances, Wu, Li, Poeschla, Eric, Bushman, Frederic D., Fuchs, James R., Kvaratskhelia, Mamuka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038613/
https://ncbi.nlm.nih.gov/pubmed/24874515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004171
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