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HIV-1 Integrase Multimerization as a Therapeutic Target

Multimeric HIV-1 integrase (IN) plays an essential, multifunctional role in virus replication and serves as an important therapeutic target. Structural and biochemical studies have revealed the importance of the ordered interplay between IN molecules for its function. In the presence of viral DNA en...

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Detalhes bibliográficos
Publicado no:Curr Top Microbiol Immunol
Main Authors: Feng, Lei, Larue, Ross C., Slaughter, Alison, Kessl, Jacques J., Kvaratskhelia, Mamuka
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4791179/
https://ncbi.nlm.nih.gov/pubmed/25778682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2015_439
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