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Methods for the Analyses of Inhibitor-Induced Aberrant Multimerization of HIV-1 Integrase
HIV-1 integrase (IN) is an important therapeutic target as its function is essential for the viral lifecycle. The discovery of multifunctional allosteric IN inhibitors or ALLINIs, which potently impair viral replication by promoting aberrant, higher order IN multimerization as well as inhibit IN int...
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| Publicado no: | Methods Mol Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4793731/ https://ncbi.nlm.nih.gov/pubmed/26714710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3046-3_10 |
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