A New Class of Multimerization Selective Inhibitors of HIV-1 Integrase

The quinoline-based allosteric HIV-1 integrase (IN) inhibitors (ALLINIs) are promising candidates for clinically useful antiviral agents. Studies using these compounds have highlighted the role of IN in both early and late stages of virus replication. However, dissecting the exact mechanism of actio...

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Bibliografiske detaljer
Main Authors: Sharma, Amit, Slaughter, Alison, Jena, Nivedita, Feng, Lei, Kessl, Jacques J., Fadel, Hind J., Malani, Nirav, Male, Frances, Wu, Li, Poeschla, Eric, Bushman, Frederic D., Fuchs, James R., Kvaratskhelia, Mamuka
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038613/
https://ncbi.nlm.nih.gov/pubmed/24874515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004171
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