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NADH Binds and Stabilizes the 26S Proteasomes Independent of ATP
The 26S proteasome is the end point of the ubiquitin- and ATP-dependent degradation pathway. The 26S proteasome complex (26S PC) integrity and function has been shown to be highly dependent on ATP and its homolog nucleotides. We report here that the redox molecule NADH binds the 26S PC and is suffic...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036265/ https://ncbi.nlm.nih.gov/pubmed/24596095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537175 |
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