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Robust and accurate prediction of residue–residue interactions across protein interfaces using evolutionary information

Do the amino acid sequence identities of residues that make contact across protein interfaces covary during evolution? If so, such covariance could be used to predict contacts across interfaces and assemble models of biological complexes. We find that residue pairs identified using a pseudo-likeliho...

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書誌詳細
主要な著者: Ovchinnikov, Sergey, Kamisetty, Hetunandan, Baker, David
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034769/
https://ncbi.nlm.nih.gov/pubmed/24842992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02030
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