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Assessing the utility of coevolution-based residue–residue contact predictions in a sequence- and structure-rich era
Recently developed methods have shown considerable promise in predicting residue–residue contacts in protein 3D structures using evolutionary covariance information. However, these methods require large numbers of evolutionarily related sequences to robustly assess the extent of residue covariation,...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785744/ https://ncbi.nlm.nih.gov/pubmed/24009338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314045110 |
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