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Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4

Members of the Zrt and Irt protein (ZIP) family are a central participant in transition metal homeostasis as they function to increase the cytosolic concentration of zinc and/or iron. However, the lack of a crystal structure hinders elucidation of the molecular mechanism of ZIP proteins. Here, we em...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Antala, Sagar, Ovchinnikov, Sergey, Kamisetty, Hetunandan, Baker, David, Dempski, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505028/
https://ncbi.nlm.nih.gov/pubmed/25971965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.617613
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