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Large-scale determination of previously unsolved protein structures using evolutionary information

The prediction of the structures of proteins without detectable sequence similarity to any protein of known structure remains an outstanding scientific challenge. Here we report significant progress in this area. We first describe de novo blind structure predictions of unprecendented accuracy we mad...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ovchinnikov, Sergey, Kinch, Lisa, Park, Hahnbeom, Liao, Yuxing, Pei, Jimin, Kim, David E, Kamisetty, Hetunandan, Grishin, Nick V, Baker, David
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4602095/
https://ncbi.nlm.nih.gov/pubmed/26335199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09248
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