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Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans
DNA lesions that block replication fork progression are drivers of cancer-associated genome alterations, but the error-prone DNA repair mechanisms acting on collapsed replication are incompletely understood, and their contribution to genome evolution largely unexplored. Here, through whole-genome se...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4032859/ https://ncbi.nlm.nih.gov/pubmed/24614976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.170431.113 |
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