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Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells

Ring chromosomes are structural aberrations commonly associated with birth defects, mental disabilities, and growth retardation(1,2). Rings form upon fusion of the long and short arms of a chromosome, sometimes associated with large terminal deletions(2). Due to the severity of these large-scale abe...

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Autors principals: Bershteyn, Marina, Hayashi, Yohei, Desachy, Guillaume, Hsiao, Edward C., Sami, Salma, Tsang, Kathryn M., Weiss, Lauren A., Kriegstein, Arnold R., Yamanaka, Shinya, Wynshaw-Boris, Anthony
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030630/
https://ncbi.nlm.nih.gov/pubmed/24413397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12923
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