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Chromosome therapy: Correction of large chromosomal aberrations by inducing ring chromosomes in induced pluripotent stem cells (iPSCs)
The fusion of the short (p) and long (q) arms of a chromosome is referred to as a “ring chromosome.” Ring chromosome disorders occur in approximately 1 in 50 000–100 000 patients. Ring chromosomes can result in birth defects, mental disabilities, and growth retardation if additional genes are delete...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164482/ https://ncbi.nlm.nih.gov/pubmed/25482192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.36300 |
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