The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis

BACKGROUND: Osteosarcoma is the most frequent primary malignant bone tumor, notorious for its lung metastasis. Shikonin, an effective constituent extracted from Chinese medicinal herb, was demonstrated to induce necroptosis in some cancers. METHODS: MTT assay was performed to detect cell survival ra...

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Detaylı Bibliyografya
Asıl Yazarlar: Fu, Zeze, Deng, Biyong, Liao, Yuxin, Shan, Liancheng, Yin, Fei, Wang, Zhuoying, Zeng, Hui, Zuo, Dongqing, Hua, Yingqi, Cai, Zhengdong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028842/
https://ncbi.nlm.nih.gov/pubmed/24314238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-580
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