Sarcoma-Targeting Peptide-Decorated Polypeptide Nanogel Intracellularly Delivers Shikonin for Upregulated Osteosarcoma Necroptosis and Diminished Pulmonary Metastasis

Purpose: Osteosarcoma is the most common primary bone cancer and is notorious for pulmonary metastasis, representing a major threat to pediatric patients. An effective drug targeting osteosarcoma and its lung metastasis is urgently needed. Design: In this study, a sarcoma-targeting peptide-decorated...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Li, Suoyuan, Zhang, Tao, Xu, Weiguo, Ding, Jianxun, Yin, Fei, Xu, Jing, Sun, Wei, Wang, Hongsheng, Sun, Mengxiong, Cai, Zhengdong, Hua, Yingqi
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5835942/
https://ncbi.nlm.nih.gov/pubmed/29507626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.18299
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