Shikonin promotes adriamycin-induced apoptosis by upregulating caspase-3 and caspase-8 in osteosarcoma

Osteosarcoma is the most common primary malignant bone tumor. Cancer cells employ a host of mechanisms to develop resistance to adriamycin (ADM) or other chemotherapeutic drugs. Shikonin (SK), an active constituent extracted from a Chinese medicinal herb, has been shown to cooperate with ADM in the...

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Udgivet i:Mol Med Rep
Main Authors: Yang, Qing, Li, Suoyuan, Fu, Zeze, Lin, Binhui, Zhou, Zifei, Wang, Zhuoying, Hua, Yingqi, Cai, Zhengdong
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2017
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562087/
https://ncbi.nlm.nih.gov/pubmed/28627658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2017.6729
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