Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation

Necroptosis is a type of programmed necrosis regulated by receptor interacting protein kinase 1 (RIP1) and RIP3. Necroptosis is found to be accompanied by an overproduction of reactive oxygen species (ROS), but the role of ROS in regulation of necroptosis remains elusive. In this study, we investiga...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Pharmacol Sin
Egile Nagusiak: LU, Bin, GONG, Xu, WANG, Zong-qi, DING, Ye, WANG, Chen, LUO, Tian-fei, PIAO, Mei-hua, MENG, Fan-kai, CHI, Guang-fan, LUO, Yi-nan, GE, Peng-fei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5672068/
https://ncbi.nlm.nih.gov/pubmed/28816233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.112
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