Design, Synthesis, and Pharmacological Evaluation of Fluorescent and Biotinylated Antagonists of ρ(1) GABA(C) Receptors

[Image: see text] The ρ(1) GABA(C) receptor is a ligand-gated chloride ion channel that shows promise as a therapeutic target for myopia, sleep disorders, memory and learning facilitation, and anxiety-related disorders. As such, there is a need for molecular probes to understand the role GABA(C) rec...

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Hlavní autoři: Gavande, Navnath, Kim, Hye-Lim, Doddareddy, Munikumar R., Johnston, Graham A. R., Chebib, Mary, Hanrahan, Jane R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2013
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027487/
https://ncbi.nlm.nih.gov/pubmed/24900684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300476v
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