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The Antituberculosis Antibiotic Capreomycin Inhibits Protein Synthesis by Disrupting Interaction between Ribosomal Proteins L12 and L10

Capreomycin is a second-line drug for multiple-drug-resistant tuberculosis (TB). However, with increased use in clinics, the therapeutic efficiency of capreomycin is decreasing. To better understand TB resistance to capreomycin, we have done research to identify the molecular target of capreomycin....

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Detalhes bibliográficos
Main Authors: Lin, Yuan, Li, Yan, Zhu, Ningyu, Han, Yanxing, Jiang, Wei, Wang, Yanchang, Si, Shuyi, Jiang, Jiandong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023752/
https://ncbi.nlm.nih.gov/pubmed/24449778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02394-13
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