The Antituberculosis Antibiotic Capreomycin Inhibits Protein Synthesis by Disrupting Interaction between Ribosomal Proteins L12 and L10

Capreomycin is a second-line drug for multiple-drug-resistant tuberculosis (TB). However, with increased use in clinics, the therapeutic efficiency of capreomycin is decreasing. To better understand TB resistance to capreomycin, we have done research to identify the molecular target of capreomycin....

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Bibliographische Detailangaben
Hauptverfasser: Lin, Yuan, Li, Yan, Zhu, Ningyu, Han, Yanxing, Jiang, Wei, Wang, Yanchang, Si, Shuyi, Jiang, Jiandong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
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Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023752/
https://ncbi.nlm.nih.gov/pubmed/24449778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02394-13
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