The Antituberculosis Antibiotic Capreomycin Inhibits Protein Synthesis by Disrupting Interaction between Ribosomal Proteins L12 and L10

Capreomycin is a second-line drug for multiple-drug-resistant tuberculosis (TB). However, with increased use in clinics, the therapeutic efficiency of capreomycin is decreasing. To better understand TB resistance to capreomycin, we have done research to identify the molecular target of capreomycin....

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Bibliografiske detaljer
Main Authors: Lin, Yuan, Li, Yan, Zhu, Ningyu, Han, Yanxing, Jiang, Wei, Wang, Yanchang, Si, Shuyi, Jiang, Jiandong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023752/
https://ncbi.nlm.nih.gov/pubmed/24449778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02394-13
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