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The Antituberculosis Antibiotic Capreomycin Inhibits Protein Synthesis by Disrupting Interaction between Ribosomal Proteins L12 and L10

Capreomycin is a second-line drug for multiple-drug-resistant tuberculosis (TB). However, with increased use in clinics, the therapeutic efficiency of capreomycin is decreasing. To better understand TB resistance to capreomycin, we have done research to identify the molecular target of capreomycin....

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Autori principali: Lin, Yuan, Li, Yan, Zhu, Ningyu, Han, Yanxing, Jiang, Wei, Wang, Yanchang, Si, Shuyi, Jiang, Jiandong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023752/
https://ncbi.nlm.nih.gov/pubmed/24449778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02394-13
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