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The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome
Viomycin and capreomycin belong to the tuberactinomycin family of antibiotics, which are among the most effective antibiotics against multidrug-resistant tuberculosis. Here we present two crystal structures of the 70S ribosome complexed with three tRNAs and bound to either viomycin or capreomycin at...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2917106/ https://ncbi.nlm.nih.gov/pubmed/20154709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1755 |
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