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The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome

Viomycin and capreomycin belong to the tuberactinomycin family of antibiotics, which are among the most effective antibiotics against multidrug-resistant tuberculosis. Here we present two crystal structures of the 70S ribosome complexed with three tRNAs and bound to either viomycin or capreomycin at...

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Bibliografiske detaljer
Main Authors: Stanley, Robin E., Blaha, Gregor, Grodzicki, Robert L., Strickler, Michael D., Steitz, Thomas A.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2917106/
https://ncbi.nlm.nih.gov/pubmed/20154709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1755
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