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The Antituberculosis Antibiotic Capreomycin Inhibits Protein Synthesis by Disrupting Interaction between Ribosomal Proteins L12 and L10

Capreomycin is a second-line drug for multiple-drug-resistant tuberculosis (TB). However, with increased use in clinics, the therapeutic efficiency of capreomycin is decreasing. To better understand TB resistance to capreomycin, we have done research to identify the molecular target of capreomycin....

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Autores principales: Lin, Yuan, Li, Yan, Zhu, Ningyu, Han, Yanxing, Jiang, Wei, Wang, Yanchang, Si, Shuyi, Jiang, Jiandong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023752/
https://ncbi.nlm.nih.gov/pubmed/24449778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02394-13
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