Mycobacterium tuberculosis Hip1 Modulates Macrophage Responses through Proteolysis of GroEL2

Mycobacterium tuberculosis (Mtb) employs multiple strategies to evade host immune responses and persist within macrophages. We have previously shown that the cell envelope-associated Mtb serine hydrolase, Hip1, prevents robust macrophage activation and dampens host pro-inflammatory responses, allowi...

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Detalhes bibliográficos
Main Authors: Naffin-Olivos, Jacqueline L., Georgieva, Maria, Goldfarb, Nathan, Madan-Lala, Ranjna, Dong, Lauren, Bizzell, Erica, Valinetz, Ethan, Brandt, Gabriel S., Yu, Sarah, Shabashvili, Daniil E., Ringe, Dagmar, Dunn, Ben M., Petsko, Gregory A., Rengarajan, Jyothi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022732/
https://ncbi.nlm.nih.gov/pubmed/24830429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004132
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